Recognition and management of neuropsychiatric complications in Parkinson's disease.
Identifieur interne : 002715 ( Main/Exploration ); précédent : 002714; suivant : 002716Recognition and management of neuropsychiatric complications in Parkinson's disease.
Auteurs : Florian Ferreri [Canada] ; Catherine Agbokou ; Serge GauthierSource :
- CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne [ 1488-2329 ] ; 2006.
English descriptors
- KwdEn :
- Cognition Disorders (diagnosis), Cognition Disorders (etiology), Cognition Disorders (therapy), Fatigue, Gambling, Humans, Mental Disorders (diagnosis), Mental Disorders (etiology), Mental Disorders (therapy), Parkinson Disease (complications), Parkinson Disease (psychology), Risk Factors, Sexuality, Sleep Wake Disorders (diagnosis), Sleep Wake Disorders (etiology), Sleep Wake Disorders (therapy), Substance-Related Disorders (etiology).
- MESH :
- complications : Parkinson Disease.
- diagnosis : Cognition Disorders, Mental Disorders, Sleep Wake Disorders.
- etiology : Cognition Disorders, Mental Disorders, Sleep Wake Disorders, Substance-Related Disorders.
- psychology : Parkinson Disease.
- therapy : Cognition Disorders, Mental Disorders, Sleep Wake Disorders.
- Fatigue, Gambling, Humans, Risk Factors, Sexuality.
Abstract
Parkinson's disease is primarily considered a motor disease characterized by rest tremor, rigidity, bradykinesia and postural disturbances. However, neuropsychiatric complications, including mood and anxiety disorders, fatigue, apathy, psychosis, cognitive impairment, dementia, sleep disorders and addictions, frequently complicate the course of the illness. The pathophysiologic features of these complications are multifaceted and include neuropathophysiologic changes of a degenerative disease, exposure to antiparkinsonian treatments and emotional reactions to having a disabling chronic illness. Changes in mental status have profound implications for the well-being of patients with Parkinson's disease and of their caregivers. Treatment is often efficacious but becomes a challenge in advanced stages of Parkinson's disease. In this article, we review the key clinical features of neuropsychiatric complications in Parkinson's disease as well as what is known about their epidemiologic characteristics, risk factors, pathophysiologic features and management.
DOI: 10.1503/cmaj.060542
PubMed: 17146092
Affiliations:
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Le document en format XML
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uniqKey="Gauthier S" first="Serge" last="Gauthier">Serge Gauthier</name></author></analytic><series><title level="j">CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne</title><idno type="eISSN">1488-2329</idno><imprint><date when="2006" type="published">2006</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Cognition Disorders (diagnosis)</term><term>Cognition Disorders (etiology)</term><term>Cognition Disorders (therapy)</term><term>Fatigue</term><term>Gambling</term><term>Humans</term><term>Mental Disorders (diagnosis)</term><term>Mental Disorders (etiology)</term><term>Mental Disorders (therapy)</term><term>Parkinson Disease (complications)</term><term>Parkinson Disease (psychology)</term><term>Risk Factors</term><term>Sexuality</term><term>Sleep Wake Disorders (diagnosis)</term><term>Sleep Wake Disorders (etiology)</term><term>Sleep Wake Disorders (therapy)</term><term>Substance-Related Disorders (etiology)</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Cognition Disorders</term><term>Mental Disorders</term><term>Sleep Wake Disorders</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Cognition Disorders</term><term>Mental Disorders</term><term>Sleep Wake Disorders</term><term>Substance-Related Disorders</term></keywords><keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Cognition Disorders</term><term>Mental Disorders</term><term>Sleep Wake Disorders</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Fatigue</term><term>Gambling</term><term>Humans</term><term>Risk Factors</term><term>Sexuality</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Parkinson's disease is primarily considered a motor disease characterized by rest tremor, rigidity, bradykinesia and postural disturbances. However, neuropsychiatric complications, including mood and anxiety disorders, fatigue, apathy, psychosis, cognitive impairment, dementia, sleep disorders and addictions, frequently complicate the course of the illness. The pathophysiologic features of these complications are multifaceted and include neuropathophysiologic changes of a degenerative disease, exposure to antiparkinsonian treatments and emotional reactions to having a disabling chronic illness. Changes in mental status have profound implications for the well-being of patients with Parkinson's disease and of their caregivers. Treatment is often efficacious but becomes a challenge in advanced stages of Parkinson's disease. In this article, we review the key clinical features of neuropsychiatric complications in Parkinson's disease as well as what is known about their epidemiologic characteristics, risk factors, pathophysiologic features and management.</div></front></TEI><affiliations><list><country><li>Canada</li></country></list><tree><noCountry><name sortKey="Agbokou, Catherine" sort="Agbokou, Catherine" uniqKey="Agbokou C" first="Catherine" last="Agbokou">Catherine Agbokou</name><name sortKey="Gauthier, Serge" sort="Gauthier, Serge" uniqKey="Gauthier S" first="Serge" last="Gauthier">Serge Gauthier</name></noCountry><country name="Canada"><noRegion><name sortKey="Ferreri, Florian" sort="Ferreri, Florian" uniqKey="Ferreri F" first="Florian" last="Ferreri">Florian Ferreri</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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